INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)
Department of Health and Human Services · Opportunity RFA-OD-27-005
At a glance AI extracted
INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required) (National Institutes of Health) Est. $3,000,000
Who can apply
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clar…
- Public housing authorities/Indian housing authorities
- Native American tribal governments (Federally recognized)
Eligible uses
- Health
Typical documents
- Application form (SF-424)
- Project narrative
- Detailed budget
| Award size | Est. $3,000,000 |
|---|---|
| Number of awards | 4 |
| Deadline | 2028-06-15 |
| Posted | 2026-05-13 |
| Eligible applicants | For profit organizations other than small businesses, Small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Public housing authorities/Indian housing authorities, Native American tribal governments (Federally recognized), State governments, Special district governments, County governments, Nonprofits that do not have a 501(c)(3) status with t… |
| Activity | Health |
| Funding instrument | Grant |
| CFDA program | Research Related to Deafness and Communication Disorders / National Center on Sleep Disorders Research / Trans-NIH Research Support |
| Org type filter | Nonprofit / For-profit / State Gov / Local Gov / Tribal Gov / Individual / K-12AI-tagged |
| Sector filter | Health / Research / Education / Tech / Community / InfrastructureAI-tagged |
| Use filter | Research / Training / PlanningAI-tagged |
| Source | grants.gov |
| Last updated | 2026-05-14T14:08:51.538023+00:00 |
From the official announcement
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this NOFO may not exceed five years. This NOFO provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33) of up to three years, although the total duration of the award may not exceed five years. This NOFO requires measurable R61 milestones. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Agency contact
National Institutes of Health
This page summarizes public information from grants.gov via AI extraction. Final eligibility and application terms are set by the issuing agency. AI summaries may contain errors. Verify on the official announcement before applying.